Mechanisms of endogenous repair failure during intervertebral disc degeneration
نویسندگان
چکیده
منابع مشابه
Increased caveolin-1 in intervertebral disc degeneration facilitates repair.
BACKGROUND Preceding intervertebral disc (IVD) degeneration, the cell phenotype in the nucleus pulposus (NP) shifts from notochordal cells (NCs) to chondrocyte-like cells (CLCs). Microarray analysis showed a correlation between caveolin-1 expression and the phenotypic transition of NCs to CLCs. With a clinical directive in mind, the aim of this study was to determine the role of caveolin-1 in I...
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چکیده ندارد.
15 صفحه اولSodium MRI of Intervertebral Disc Degeneration
Objective: To establish sodium MRI as a non-invasive method for measuring intervertebral disc proteoglycan content Introduction: Intervertebral disc (IVD) degeneration is a common and sometimes debilitating condition, incurring tremendous financial cost on society. The initial stage of IVD degeneration involves the breakdown of proteoglycans (PG) in the nucleus pulposus (NP) region of the disc[...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2019
ISSN: 1063-4584
DOI: 10.1016/j.joca.2018.08.021